Ophthalmological findings and multimodal imaging of PVRL. (A) Slit-lamp examination showing a quiet anterior chamber with no protein flare and some cellular gray diffuse keratic precipitates (white arrows). (B) A clump of lymphoma cells is visible in the slit-lamp examination in the anterior vitreous or along the vitreous fibrils (yellow arrow). (C) At diagnosis, a fundus examination reveals only subtle small yellowish retinal lesions (white arrow). (D) The (sub)retinal lesions detected at diagnosis are more extended and multifocal (yellow arrow; composite color fundus photograph, with photos merged together with built-in camera software) (E) Retinal photograph showing cream-colored subretinal deposits (white asterisks). (F) Infrared photograph of the same patient shown in panel E, showing hyperreflective lesions corresponding to the lesions visible in panel E (white asterisks). (G) Fluorescein angiography of the same patient shown in panel E, showing the lymphoid infiltration as dark spots masking the underlying fluorescence of the choroid (white asterisks). RPE alterations appear as hyperfluorescent areas because of window effects (yellow arrow). (H) Indocyanine angiography of the same patient shown in panel E, with poorly contributive hypocyanescent lesions visualized. (I) Fundus photograph showing patchy yellowish subretinal lesions (white asterisk). (J) OCT image of the retina along the white line in panel I showing subretinal hyperreflective deposits of lymphoma cells (white asterisk) that are located between the RPE (yellow arrow) and the Bruch membrane (white arrow).