Figure 5.
Molecular response after 2 courses of treatment in relapsed DLBCL. (A) Waterfall plot of the log-fold change in ctDNA load after 2 courses of treatment in relapsed DLBCL. Levels of ctDNA are normalized to baseline levels. The dashed line tracks the −2-log threshold. Each column represents a patient and is color coded according to the depth of reduction in ctDNA load. (B) Best response to treatment according to the log-fold change in ctDNA load after 2 courses of treatment in relapsed DLBCL. (C) Kaplan-Meier curves of PFS stratified according to the log-fold change in ctDNA load after 2 courses of treatment in relapsed DLBCL. Red, <2-log-fold change in ctDNA load; blue: >2-log–fold change in ctDNA load. CR, complete response; NA, not applicable; PD, progressive disease; PR, partial response; SD, stable disease.

Molecular response after 2 courses of treatment in relapsed DLBCL. (A) Waterfall plot of the log-fold change in ctDNA load after 2 courses of treatment in relapsed DLBCL. Levels of ctDNA are normalized to baseline levels. The dashed line tracks the −2-log threshold. Each column represents a patient and is color coded according to the depth of reduction in ctDNA load. (B) Best response to treatment according to the log-fold change in ctDNA load after 2 courses of treatment in relapsed DLBCL. (C) Kaplan-Meier curves of PFS stratified according to the log-fold change in ctDNA load after 2 courses of treatment in relapsed DLBCL. Red, <2-log-fold change in ctDNA load; blue: >2-log–fold change in ctDNA load. CR, complete response; NA, not applicable; PD, progressive disease; PR, partial response; SD, stable disease.

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