Zebrafish efl1 morphants model human SDS features. (A-B) Cell death (A) and neutrophil production (B) of zebrafish embryos 48 hours post fertilization by the knockdown of efl1 and sbds. (C-E) Rescue of efl1 MO animals using human EFL1^WT or EFL1^p.Thr1069Ala RNA, documenting morphology (C), hemoglobin production (D), and neutrophil production (E). **P < .01, ***P < .0005, ****P < .0001. MO, morpholino; n.s., not significant; WT, wild type.