AB023 blunts dialysis associated plasma CRP generation. Time course of plasma CRP on study day 1 predose through 48 hours postdose expressed as the percentage of control of baseline (predose) in the placebo group (red circles), the 0.25 mg/kg group (blue circles), and the 0.5 mg/kg group (light green circles). CRP induction at 24 hours postdose is significantly blunted in the 0.5 mg/kg group compared with placebo. Data are mean ± SEM. *P < .05 for the 0.5 mg/kg group compared with placebo.