Competitive transplantation assay performed on whole BM (WBM) isolated from LPS-stimulated LeprCre;Il6^fl/fl and control mice. (A) Experimental scheme depicting specifics of the competitive transplantations assay. (B) Results of the competitive transplantation assay performed according to the scheme depicted in panel A. Results indicate peripheral blood chimerism at weeks 4, 8, 12, and 16 as determined by the percentage of CD45.2⁺ donor cells. Blue dots indicate WT recipient mice given WBM from PBS-treated donor mice, and red dots indicate WT recipient mice given WBM from LPS-treated donor mice. *P < .05, **P < .01. i.p., intraperitoneal; ns, nonsignificant; PB, peripheral blood.