Figure 1.
Kinetics of B cells and normal plasma cell recovery in patients treated with anti-BCMA CAR T cells. (A) Median counts of B lymphocytes at different time points before and after CAR T-cell infusion. Box-and-whisker plots show the median (horizontal line) and interquartile range (box). Dotted lines indicate the normal range. (B-C) Cumulative incidence of B-cell count returning to baseline (B) and normal (C) levels after anti-BCMA CAR T-cell therapy. (D) Cumulative incidence of normal plasma cells redetected in bone marrow after anti-BCMA CAR T-cell therapy. The significance of results was calculated by the Kruskal-Wallis test. *P < .05, **P < .01, ***P < .001, compared with baseline pretherapy levels.