Figure 2.
Markers of impaired hematopoietic reserve, inflammation, and tumor microenvironment are significantly correlated with the duration of neutropenia. Univariate analysis of the influence of the baseline platelet count (A), hemoglobin (Hb) (B), ANC (C), C-reactive protein (CRP) (D), ferritin (E), and BM infiltration (F) on the duration of severe neutropenia (ANC <500 cells per µL) between days 0 and 60 in the training cohort (n = 55). The data concerning BM infiltration was studied via logistic regression analysis; P value is shown for the likelihood ratio test (G2); light shading indicates the 95% asymptotic confidence bands. (A-E) The Spearman correlation coefficient (r) and the respective P values are provided. A positive r value indicates a positive correlation and a negative r value indicates a negative correlation. Light shading indicates the 95% confidence bands of the best-fit line from the simple linear regression. B-NHL, B-cell non-Hodgkin lymphoma.