Circos plots confirming monoclonality of FACS Sézary tumor subsets given their monoclonal TRs of the α and β chains. By contrast, corresponding normal CD4⁺ T-cell subsets isolated from the same patients with SS revealed a typical polyclonal pattern. The extended figure of rearrangement patterns (circos plots), clonality distribution (pie charts), and sample information regarding TRA/TRB rearrangements and CDR3 sequences for all FACS CD4⁺ T-cell subsets are depicted in supplemental Figures 2 and 3 and supplemental Table 2, respectively.