CONSORT diagram outlining outcomes for the 82 patients registered to the ALLG ALL06 study. *Four patients were excluded: 1 with failed diagnostic karyotype and fluorescent in situ hybridization analysis and found to be BCR-ABL positive on polymerase chain reaction (PCR) testing; 1 with B-cell lymphoblastic lymphoma (B-LBL) without evidence of BM involvement; 1 with ambiguous lineage acute leukemia; and 1 with synchronous T-cell ALL (T-ALL) and T-cell–rich large cell lymphoma.