MRD levels by time points and 12-month CR status. MRD data after progression are not included. MRD levels from the same patients are connected by lines. All IR-treated patients with MRD data (A); all FCR-treated patients with MRD data (B); IR-treated patients in CR at the 12-month response evaluation (C); FCR-treated patients in CR at the 12-month response evaluation (D); IR-treated patients not in CR at the 12-month response evaluation (E); and FCR-treated patients not in CR at the 12-month response evaluation (F). uMRD, undetectable MRD.