Treatment and responses in patients with relapse in the EPAG-IST group. (A) Approximately half of the relapsed patients were treated with CSA alone, and the other half were treated with CSA and EPAG combination. Responses in these 2 groups are shown in the pie diagram. *One patient in the CSA plus EPAG treated group was non-compliant, and therefore not assessable and not included in the pie diagram. (B) Of the 43 subjects who achieved a response with reinitiation of oral therapy, about 1/3 were able to discontinue drug with ongoing response while another 1/3 remained on drug (many on low dose or being tapered) with ongoing response.