Figure 4.
![ASNS methylation status in pediatric patients with T-ALL. (A) Correlation between methylation level of ASNS and that of 7 genes located in the 7q21 imprinted gene cluster in 77 childhood T-ALL samples of the TCCSG and JACLS cohorts (DNA Data Bank of Japan [JGAS00000000138]).23 The vertical axes indicate mean percent methylation of ASNS, and the horizontal axes indicate mean percent methylation of each gene. The correlation coefficients and P values in the Spearman correlation test are indicated. (B) Association of ASNS methylation status with ASNS gene expression in 77 childhood T-ALL samples of the TCCSG and JACLS cohorts. Correlation coefficient and P value in the Spearman correlation test are shown.](https://ash.silverchair-cdn.com/ash/content_public/journal/bloodadvances/6/1/10.1182_bloodadvances.2021004271/4/advancesadv2021004271f4.png?Expires=1735804471&Signature=d0wwB~T4MT1fuIW-~pEP5BywS-hT~YiCjFp~TpRQWwIWotM5xrvKE6G67Kxg-jlh5oTWyx2bk07IgAesd5ozawV-zjVa2-gOhhANx50toCA3mC6GjeLuymPY7q3RAVsjTOXU2qHlkeP~DMhwXZ34TfmENyZRExdl5mOyttY~9-FKdKoAIjLVVCbOvE21JUazFQ-54coHO5dl2ofkDfjHvf5BWFfRsZ1G1hjy0sNIS1AGsVsqTOZULlG2KPTJWFVuMdPB7pX4NEPHaVWjS0dWdpeiqdHTMSPhCakrkRh1zay7hObUAqQAYkegDTfDwxicMpcQnmndslyEWY30wGohDA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
ASNS methylation status in pediatric patients with T-ALL. (A) Correlation between methylation level of ASNS and that of 7 genes located in the 7q21 imprinted gene cluster in 77 childhood T-ALL samples of the TCCSG and JACLS cohorts (DNA Data Bank of Japan [JGAS00000000138]).23 The vertical axes indicate mean percent methylation of ASNS, and the horizontal axes indicate mean percent methylation of each gene. The correlation coefficients and P values in the Spearman correlation test are indicated. (B) Association of ASNS methylation status with ASNS gene expression in 77 childhood T-ALL samples of the TCCSG and JACLS cohorts. Correlation coefficient and P value in the Spearman correlation test are shown.