Cytological and cytogenetic presentations of del(11q) MDS. (A-D) May-Grünwald Giemsa staining of del(11q) bone marrow. Megakaryocytes were often large and plurinucleated (A, B, and C, original magnification x×50) giving an aspect of ball bags (C) and, when associated to 5q deletion, presence of small and nonlobated megakaryocytes ([D], original magnification ×100). (E) Cytogenetic presentations of del(11q). The 2 main types of del(11q) on R-banded partial karyotypes from 2 representative cases, from left to right: large deletion, del(11)(q14q24), in case #19 and small deletion, del(11)(q22q24), in case #86.