Frequency of grade 3/4 toxicities. (A) Hematological toxicities and infections. (B) Nonhematological toxicities other than infections. No grade 3/4 pleural effusion or QTc elongation were reported. CMV, XXX; DIC, disseminated intravascular coagulopathy; PN, peripheral neuropathy; Tbil, total bilirubin; TLS, tumor lysis syndrome.