Mutational analysis for significantly mutated genes, network propagation and mutational overlap with related entities. Significance levels for all PBL MutSigCV genes (P < .01) (A) and HALLMARK gene sets and Nfkb pathway enrichment (B) for network diffusion analysis of significant MutSigCV genes (MutSigCV, P < .01). (C) UpSet plot showing the overlap of MutSigCV genes using PBL, DLBCL (1144 cases retrieved from 5 cohorts encompassing various subtypes of DLBCL via cBioPortal),^42,58–61  and MM (205 cases from Lohr et al⁶²  retrieved via cBioPortal) data; inlet shows the overlap between the 3 tumor entities.