Figure 1.
Molecular characterization of XABCLs. (A) Gene mutations in 25 XABCLs and the matched NSCLC tumors from which the XABCLs were derived. Only samples with mutations shown in the co-oncoplot were presented in the graph. Detailed mutation information for 25 pairs of samples is shown in supplemental Table 2. (B) RNA transcripts of type I and type II EBV detected in RNA-seq data of 15 XABCLs. LMP1 and EBNA2 were detected in all 15 samples, suggesting that XABCLs have type II or type III latency of EBV infection.