Transcriptome profiling according to CEBPA mutational status. (A) Gene expression clustering according to mutational status with CEBPA-mutant samples compared with other molecular alterations that have prognostic implications in pediatric AML. (B-C) Unsupervised hierarchical clustering of patients according to CEBPA mutational status (B) and with CEBPA-bZip and double mutations (C). (D) CEBPA mutational status and association with CEBPA transcript expression. mut, mutation; TPM, transcripts per million.