PFS by baseline MTV. (A) PFS by high (blue) vs low (red) MTV, using a cutoff of 60 mL. (B) PFS by change to MTV with bridging therapy using a cutoff of 60 mL. Low MTV to low MTV (red), high MTV to low MTV (blue), and high MTV to high MTV (light green). *Pairwise P value low to low MTV compared with high to high MTV.