Figure 1.
DLBCL in individuals infected by HIV. Systemic DLBCL with immunoblastic-plasmacytoid features, expressing the CD20+, CD10−, BCL6−, MUM1/IRF4+, CD138+, and CD38+ profile. (A) Hematoxylin-eosin stain (H&E) shows that most tumor cells display large cytoplasms and round or oval nuclei with large nucleoli. Tumor cells express cytoplasmic staining for CD138 (red). The H&E stain (inset) shows that the morphology of immunostained cells is immunoblastic. (B) Tumor cells express cytoplasmic and membranous staining for CD38 (brown). CD138 and CD38 immunohistochemistry, hematoxylin counterstain. Original magnification, ×400. Images were taken using a Nikon Eclipse 80i microscope with a Plan Fluor 40×/0.75 objective and Nikon digital sight DS-Fi1 camera equipped with control unit-DS-L2. Images were processed using Adobe Photoshop CS2 V9.0.

DLBCL in individuals infected by HIV. Systemic DLBCL with immunoblastic-plasmacytoid features, expressing the CD20+, CD10−, BCL6−, MUM1/IRF4+, CD138+, and CD38+ profile. (A) Hematoxylin-eosin stain (H&E) shows that most tumor cells display large cytoplasms and round or oval nuclei with large nucleoli. Tumor cells express cytoplasmic staining for CD138 (red). The H&E stain (inset) shows that the morphology of immunostained cells is immunoblastic. (B) Tumor cells express cytoplasmic and membranous staining for CD38 (brown). CD138 and CD38 immunohistochemistry, hematoxylin counterstain. Original magnification, ×400. Images were taken using a Nikon Eclipse 80i microscope with a Plan Fluor 40×/0.75 objective and Nikon digital sight DS-Fi1 camera equipped with control unit-DS-L2. Images were processed using Adobe Photoshop CS2 V9.0.

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