Molecular subtype clustering of patients with ALL based on gene expression signatures. (A) Hierarchical clustering and (B) experimental t-distributed stochastic neighbor embedding (tSNE) performed using the top 500 variable genes from 1134 ALL samples from both in-house and public RNA-seq data sets. (C) The neural network probability score for each of the subtypes listed for panels A-C. Results for patient #124 are shown by the arrow in A and the red dot in B.