Figure 1
Evaluation of prolonged activated partial thromboplastin time (APTT). *Differential diagnosis: 1) deficiency of coagulation factor(s) (e.g., fVIII, IX, XI, XII, prekallikrein, or high-molecular-weight kininogen); 2) heparin contamination of specimen; 3) inhibitor to a specific coagulation factor (e.g.fVIII); 4) presence of a non-specific inhibitor (e.g.. lupus anticoagulant).

Evaluation of prolonged activated partial thromboplastin time (APTT). *Differential diagnosis: 1) deficiency of coagulation factor(s) (e.g., fVIII, IX, XI, XII, prekallikrein, or high-molecular-weight kininogen); 2) heparin contamination of specimen; 3) inhibitor to a specific coagulation factor (e.g.fVIII); 4) presence of a non-specific inhibitor (e.g.. lupus anticoagulant).

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