Figure 1.
Details of published phase 2 ASH abstracts in peer-reviewed journals and reasons for discontinuation to phase 3 trials. (A) Overview of journals publishing phase 2 studies as presented at ASH from 2013 through 2015 according to the conclusion as presented in the publication. Journals with at least 2 published ASH abstracts are displayed. (B) Violin plot of 2-year 2020 impact factors of journals publishing positive, negative, and inconclusive studies initially presented at ASH according to the conclusion in the publication. (C) Overview of reasons for clinical research not progressing to randomized phase 3 despite of positive phase 2 results.