Figure 2.
Severity of hematologic toxicities. Percentage of patients with neutropenia (A), thrombocytopenia (B), and anemia (C) by post-CAR T-cell infusion day, stratified by CTCAE grade. Because of the variability in collection dates, for day = n, the minimum cell count falling within an arbitrary range of n was selected for each patient (ie, day 0 = days −7 and 0, day 14 = days 12-16, day-28 = days 23-33, day 60 = days 55-65, day 90 = days 85-95, day 120 = days 110-130, and day 180 = days 160-200). Patients were no longer included in this analysis pending receipt of a subsequent line of therapy, second CAR T-cell infusion, or withdrawal from the study.