Molecular subgroup prediction and recurrent mutated pathways in DLBCL-AE. (A) Alluvial plot shows the frequency and relationship between groups, COO classification according to LYMPH2Cx, and/or HTG and molecular subgroup prediction according to LymphGen tool¹²  of 46 cases of DLBCL-AE. The bars indicate the molecular predicted subgroup in all cases and in each genetic group identified; 57% of all cases were assigned to a specific molecular subgroup. (B) Recurrent mutated pathways²²  in 46 cases of DLBCL-AE. Genes included in each pathway are indicated in supplemental Table 1. Bar graph shows the total number of mutated cases for each pathway. Asterisk represents significant mutated pathways. AE, aberrant expressor CD10⁺BCL6⁺MUM1⁺; R, rearrangement.