Clinical impact of extracted favorable prognostic genes in the training cohort. (A) Expression of 6 favorable prognostic genes in DLBCL cell lines (n = 6), primary DLBCL specimens (n = 170), and normal LNs (n = 5), as shown in a Box and Whisker plot (dots show outliers). Cell lines analyzed were RC-K8, SU-DHL-1, SU-DHL-4, SU-DHL-9, Karpas-422, and OCI-Ly-3. Lymphoma lines showed no or little candidate gene expression, suggesting genes are expressed in microenvironmental cells. Significance was determined using the Steel-Dwass test (*P < .05, **P < .005, and ***P < .0005). (B) Kaplan-Meier curves show the duration of DFS based on expression levels of favorable candidate genes. P values were calculated by log-rank test.