Patient outcome according to ELN2017 risk stratification and FLT3/NPM1 gene interactions. (A) Two-year OS was 68.8%, 51.3%, 42.8%, and 45.8% for patients belonging to the ELN2017-FR, ELN2017-IR, ELN2017-AR, and ELN2017-NC categories, respectively. (B) Two-year DFS was 59.9%, 54.2%, 45.5%, and 40.3% for the ELN2017-FR, ELN2017-IR, ELN2017-AR, and ELN2017-NC patients.