Figure 2.
Impact of tumor gene expression in the survival of patients with AL and MM according to the resemblance with normal PC counterparts. (A) NES values based on the transcriptional profile of SLOs (ie, tonsils, SLO), PB, CD39+ (CD39+ve), and CD39− (CD39-ve) BM normal PCs, measured in these as well as in tumor PCs from patients with AL (n = 32), MGUS (n = 6), and MM (n = 32). The dashed line marks the median NES of the corresponding normal PC subset. *P < .05. (B-C) Progression-free and overall survival of patients with AL (n = 29) according to low vs high NES values corresponding to normal SLO-PCs (red, NES value above the median; green, NES values below the median). (D-E) Progression-free and overall survival of patients with MM (n = 552) according to low vs high NES values corresponding to normal PB-PCs and CD39+ BM-PCs (red, NES values above the median; green, NES values below the median).

Impact of tumor gene expression in the survival of patients with AL and MM according to the resemblance with normal PC counterparts. (A) NES values based on the transcriptional profile of SLOs (ie, tonsils, SLO), PB, CD39+ (CD39+ve), and CD39− (CD39-ve) BM normal PCs, measured in these as well as in tumor PCs from patients with AL (n = 32), MGUS (n = 6), and MM (n = 32). The dashed line marks the median NES of the corresponding normal PC subset. *P < .05. (B-C) Progression-free and overall survival of patients with AL (n = 29) according to low vs high NES values corresponding to normal SLO-PCs (red, NES value above the median; green, NES values below the median). (D-E) Progression-free and overall survival of patients with MM (n = 552) according to low vs high NES values corresponding to normal PB-PCs and CD39+ BM-PCs (red, NES values above the median; green, NES values below the median).

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