Figure 2.
Recipient genotypes of rs12559701 are associated with the risk of cGVHD in the HLA-10/10-matched sibling cohort. (A) Cumulative incidence of cGVHD according to recipient rs125597901 genotypes and gender in the replication cohort. (B) Locus-zoom plot shows -log10 (P values) for association with cGVHD in the combined discovery and replication cohorts as a function of position in a 0.5 Mb region on either side of rs12559701 on chromosome X. Correlation coefficient r2 values for linkage disequilibrium with rs12559701 are coded according to the inset. Genes within this region are displayed in the lower panel.