Figure 2.
Neurodevelopmental outcomes assessed 1 year after transplant and over time. Infants underwent developmental testing using the BSID-III at 1-year posttransplant (A-B) and at additional time points after transplant (C-G). Composite scores were assigned for motor, language, and cognitive development (A). Composite scores are classified as extremely low (≤69), borderline (70-79), low average (80-89), average (90-109), high average (110-119), superior (120-129), and very superior (≥130). Subscales were also assigned for gross motor, fine motor, receptive language, expressive language, and cognitive development (B). Growth scores (mean: 500; SD: 100; range, 200-800) were calculated using raw scores to reflect longitudinal growth independent of age14 and were helpful in showing ongoing development in infants/children with low age-based scores. Growth scores are presented for individual patients (Patients 1-5) over time for the subscales: gross motor (C), fine motor (D), receptive language (E), expressive language (F), and cognitive (G).