Change in LA test status over time. (A) Cumulative incidence of first negative LA test over time. Line shows the risk of developing at first negative LA test in the study cohort (n = 164), with the x-axis representing the time in years from study inclusion. (B) Cumulative incidence of next positive LA test after first negative LA test over time. Line reports the risk of a positive LA test after the first negative LA test in the n = 42 patients who experienced a first LA negative test and had follow-up. The x-axis represents the time elapsed since the first negative LA test. Curves were estimated with competing risk estimators. Gray shaded area represents 95% confidence interval.