ABRs (treated bleeding episodes on the last concizumab dose level) during the main + extension parts of the phase 2 concizumab trials explorer4 (HAwI, HBwI) and explorer5 (HA) by hemophilia subtype; full analysis set. Least-squares mean estimates of ABR (95% CI) are shown. The ABR estimate was based on a negative binomial regression with log of exposure time as offset and hemophilia type as factor (explorer4).