Identified risk factors predictive of the outcomes. SHAP plots on the full cohort illustrate the contribution of the most important features in predicting the clinical (mean absolute SHAP values >0.01) in 2-year outlook (A-D) and 5-year outlook (E-H). Death (A,E), treatment (B,F), treatment or infection (C,G), and infection (D,H). The cluster of features predictive of different outcomes was detected after sorting the features so that the most important features predictive of treatment appear at the top (red) and the most important features predictive of infection appear at the bottom (blue). The features more predictive of death or the composite outcome and not treatment or infection appear in the middle. ECOG, Eastern Cooperative Oncology Group; Ig, immunoglobulin.