Anti-CCR9 CAR has potent antitumor activity in a MOLT4 xenograft model of T-ALL. (A) Schematic of murine MOLT4 model. (B) Bioluminescence signal in mice in study. (C) Mass of mice in study, expressed as percentage of starting mass. (D) Survival of mice in study. n = 4 per group. Experiment performed twice; data shown from representative experiment. BLI, bioluminescence imaging; NR, not reported; OS, overall survival.