Figure 5.
![Extended knob-hole interactions affect overall visco-elastic properties of the clot (tanδ). Micro-rheology experiments were conducted by forming a fibrin clot in a capillary tube. Tan[δ] at 0.1 Hz (A) was significantly increased for γDEK, whereas the single variants were similar to WT. At 1 Hz (B) and 10 Hz (C), [tanδ] was similar to WT for all variants. Mean ± SD, N = 3. ***P < .001 compared with WT.](https://ash.silverchair-cdn.com/ash/content_public/journal/bloodadvances/6/13/10.1182_bloodadvances.2022006977/3/advancesadv2022006977f5.png?Expires=1735706228&Signature=LJ0pom2z6T21l5Y3X6P~S5vVLZAR2j8MJLZfqvYp4V9nn11FG64MjG9duYB37jdPR~iiaLhR3eSB-2ukslIOr5G22cG6TIKYP7I0LJkuJYSRy7nZ-uAQOOzGa9AKLaEuBRSIr~B0exOA3Iok7FqxuEbLvJ2uIHodCvwhl0MsMEtVFBQC92rR~Em~llWqnWm7-XqrGPQQO3m38pYuqn5bBlYlkvN7HbRkflQGKmznKN49guRXDrz5e2Pxwjti~grsoq9AAUGUaGXOhW7NefoQ2KygHNm972C8BY6faY5FBWIPlXyNOUFCDHdRsLzuCkTklLRhiQPH5VSeeJoLjlbSdw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Extended knob-hole interactions affect overall visco-elastic properties of the clot (tanδ). Micro-rheology experiments were conducted by forming a fibrin clot in a capillary tube. Tan[δ] at 0.1 Hz (A) was significantly increased for γDEK, whereas the single variants were similar to WT. At 1 Hz (B) and 10 Hz (C), [tanδ] was similar to WT for all variants. Mean ± SD, N = 3. ***P < .001 compared with WT.