Figure 3.
Distinct mutation rates and CDR3 lengths of patients with IGHV4-34, IGHV3-23, IGHV3-30, IGHV3-7, and IGHV3-74 genes. (A) IGHV mutation rate in patients with different IGHV segments. (B) Correlation between CDR3 amino acid length and IGHV mutation rate. Linear regression fit for all data is shown by the blue line. (C) Those with the IGHV3-30 gene had longer VH CDR3 lengths than other subgroups. (D) Distribution of CDR3 lengths in patients with IGHV3-23 and IGHV3-30 segments. *P < .05.