Treated spontaneous ABRs. sABRs for (A) the prior on-demand group and (B) the switch group (FAS). Figures show the proportion of patients in each bleeding category, historically and on-study, as well as mean (SD) and median (range) change from historical to on-study sABR (on-study through month 12). Historically (ie, within the past 12 months), none of the patients in the prior on-demand group had a 0 or >0 to 2 sABR.