Figure 2.
Nested case-control study design. Flowchart depicting the nested case-control study design with a selection of cases with monocytosis and control subjects from the entire evaluable Lifelines cohort (n = 144 676). *Monocytosis was defined in accordance with WHO criteria for monocytosis associated with CMML: PB monocyte counts ≥1 × 109/L and ≥10% of WBC. NGS, next-generation sequencing.

Nested case-control study design. Flowchart depicting the nested case-control study design with a selection of cases with monocytosis and control subjects from the entire evaluable Lifelines cohort (n = 144 676). *Monocytosis was defined in accordance with WHO criteria for monocytosis associated with CMML: PB monocyte counts ≥1 × 109/L and ≥10% of WBC. NGS, next-generation sequencing.

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