Preferential accumulation of myeloid progenitors in the BM of mice that received ERK2-DBP–mutant HSPCs. (A-B) Percentage and absolute number of GFP⁺/Gr1⁺ or GFP⁺/Mac1⁺ myeloid cells per 1 × 10⁶ cells in the BM and spleen of mice receiving ERK2-WT–, -KO–, and -DBP–mutant HSPCs. (C) Percentage and absolute number of GFP⁺/Ter119⁺ erythroid cells per 1 × 10⁶ cells in BM and spleen in the mice in panels A and B. (D) Percentage and absolute number of GFP⁺/CD41⁺ platelets per 1 × 10⁶ cells in BM and spleen in the same mice as in panels A and B. Data are expressed as the mean ± standard error of the mean (n = 5). *P < .05; **P < .01; ***P < .001.