Figure 2.
Immune reconstitution according to the overall response. (A) Median absolute CD4+Treg cell counts with the interquartile range. (B) Median absolute NK cell counts with the interquartile range. PR (red) and no PR (blue). (C) CD4Treg:CD4Tcon ratio at week 0 (W0) and week 1 (W1). Each line indicates individual patient’s data. Dotted lines indicate threshold values of the ratio at W0 and W1 (0.06 and 0.2, respectively). (D) Proportion of patients with CD4Treg:CD4Tcon ratio above and below the threshold at W0 and W1. (E) Percent CD4Treg subset populations. Median value of each subset. EM (blue), CM (red), naive (green), and TEMRA (purple). Number of subjects (N) at each time point is the same in every figure. *P < .05, **P < .01. ***P < .005. m, month; NR, nonresponder; R, responder.

Immune reconstitution according to the overall response. (A) Median absolute CD4+Treg cell counts with the interquartile range. (B) Median absolute NK cell counts with the interquartile range. PR (red) and no PR (blue). (C) CD4Treg:CD4Tcon ratio at week 0 (W0) and week 1 (W1). Each line indicates individual patient’s data. Dotted lines indicate threshold values of the ratio at W0 and W1 (0.06 and 0.2, respectively). (D) Proportion of patients with CD4Treg:CD4Tcon ratio above and below the threshold at W0 and W1. (E) Percent CD4Treg subset populations. Median value of each subset. EM (blue), CM (red), naive (green), and TEMRA (purple). Number of subjects (N) at each time point is the same in every figure. *P < .05, **P < .01. ***P < .005. m, month; NR, nonresponder; R, responder.

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