Construction of the Markov model. (A) Markov diagram. (B) Regimens used in each line of treatment. Bd, bortezomib and dexamethasone; EloPd, elotuzumab, pomalidomide, and dexamethasone; KRd, carfilzomib, lenalidomide, and dexamethasone; Obs, observation; R, lenalidomide.