Figure 1.
PNMZL with features reminiscent of PTFL. (A) The lymph node shows scattered large follicles with intact mantle cuffs. The germinal centers are irregular and fragmented, resembling progressive transformation of germinal centers. However, the interfollicular region is markedly expanded. (B) The atypical interfollicular infiltrate is polymorphous and is composed of small- to medium-sized lymphoid cells, some displaying plasmacytoid features. Occasional eosinophils and histiocytes are present. (C) The CD20 stain highlights increased interfollicular B cells. (D) CD3 shows admixed T cells, some of which localize to the follicle centers. BCL6 highlights the germinal centers (E), some of which show an irregular serpiginous configuration also seen with the stain for CD10 (F).