Frequent mutations in PNMZL and mutational comparison between adult NMZL and PNMZL. (A) Distribution of MAP2K1 mutations at protein level. The main protein domains are represented by larger colored boxes. (B) Distribution of TNFRSF14 mutations at protein level. Intron variants are not shown. (C) Distribution of IRF8 mutations at protein level. Domains of the protein are represented according to the UniProt database (www.uniprot.org).