Forest plots of ORR between novel SA doublets and CA in patients with R/R TCL stratified by calendar period of publication. ORR for CA (A) and ORR for novel SA and its combinations with other SA (B). Forest plots are arranged in alphabetical order by author’s last name. Squares represent estimated proportions, with the size of the squares representing the weight of each trial according to the inverse variance method. Horizontal lines through the squares indicate 95% CIs. The points of the diamond indicate the 95% CI of the pooled mean. Horizontal line at the bottom indicates the prediction interval. Blank lines indicate missing information from the trial manuscript.