Figure 4.
Shear rates after transection of the mouse spermatic artery. (A) The dot plot shows the mean blood flow velocities in the intact spermatic artery. Data are presented as the mean ± SEM, and individual symbols represent individual mice. (B-H) Injury was induced by transection of the spermatic artery of wild-type mice with microscissors. (B) The curve shows the blood flow velocities upstream of the site of injury, as a function of the time after injury. (C) The dot plot shows the maximum blood flow velocities upstream of the site of injury. Data are presented as the mean ± SEM, and individual symbols represent individual mice. (D) The dot plot shows the times after injury at which the maximum upstream blood flow velocities were reached. Data are presented as the mean ± SEM, and individual symbols represent individual mice. (E) Representative image obtained with the model, whose 3D geometry is presented in the upper right corner. The red rectangle defines the zy-section of observation. and the injury appears at the top of the cylinder mimicking the spermatic artery. At the side, the colors indicate the shear rates 8.5 seconds after transection in the zx-section. The schema in the lower right corner depicts the positions of the external space and vessel lumen with the blood flow (B.f.) in the middle. (F) The curve shows the shear rate at the edge of the wound calculated with the model, as a function of the time after injury. (G) The dot plot shows the maximum shear rates at the edge of the wound calculated with the model. Data are presented as the mean ± SEM, and individual symbols represent individual mice. (H) Representative image obtained with the model, whose 3D geometry is presented in the upper right corner. The red rectangle defines the zy-section of observation, and the injury appears at the top of the cylinder mimicking the spermatic artery. At the side, the colors indicate the elongational flows 8.5 seconds after transection in the zx-section. The schema in the lower right corner depicts the positions of the external space and vessel lumen with the blood flow in the middle.

Shear rates after transection of the mouse spermatic artery. (A) The dot plot shows the mean blood flow velocities in the intact spermatic artery. Data are presented as the mean ± SEM, and individual symbols represent individual mice. (B-H) Injury was induced by transection of the spermatic artery of wild-type mice with microscissors. (B) The curve shows the blood flow velocities upstream of the site of injury, as a function of the time after injury. (C) The dot plot shows the maximum blood flow velocities upstream of the site of injury. Data are presented as the mean ± SEM, and individual symbols represent individual mice. (D) The dot plot shows the times after injury at which the maximum upstream blood flow velocities were reached. Data are presented as the mean ± SEM, and individual symbols represent individual mice. (E) Representative image obtained with the model, whose 3D geometry is presented in the upper right corner. The red rectangle defines the zy-section of observation. and the injury appears at the top of the cylinder mimicking the spermatic artery. At the side, the colors indicate the shear rates 8.5 seconds after transection in the zx-section. The schema in the lower right corner depicts the positions of the external space and vessel lumen with the blood flow (B.f.) in the middle. (F) The curve shows the shear rate at the edge of the wound calculated with the model, as a function of the time after injury. (G) The dot plot shows the maximum shear rates at the edge of the wound calculated with the model. Data are presented as the mean ± SEM, and individual symbols represent individual mice. (H) Representative image obtained with the model, whose 3D geometry is presented in the upper right corner. The red rectangle defines the zy-section of observation, and the injury appears at the top of the cylinder mimicking the spermatic artery. At the side, the colors indicate the elongational flows 8.5 seconds after transection in the zx-section. The schema in the lower right corner depicts the positions of the external space and vessel lumen with the blood flow in the middle.

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