Figure 7.
![Insertion of the BMP6 flanking enhancer region causes the overexpression of MAP3K14. (A) Heat maps displaying the number of read clouds shared between indicated regions on chromosome 6 (chr6) and chr17. The connected green and orange arrows schematically indicate the areas joined by the SV. The type of SV is indicated. (B) Schematic representation of the derivate chromosome and tracks showing the H3K27Ac signal (median ± standard deviation [SD]) in the regions involved in the SV. (C) Expression of MAP3K14. fa+ti, templated insertion occurring in a focal amplification.](https://ash.silverchair-cdn.com/ash/content_public/journal/bloodadvances/6/17/10.1182_bloodadvances.2021006720/1/advancesadv2021006720f7.png?Expires=1736046520&Signature=L7TJLopD902uFJYbNw9orxQxLQkhtACVLo-eZS8pg2rOivbe1bMYyr~amP2mZjgVKeRCOfPlKqjnUblpx9~f81cIq4uJG5Kj3BcSlWDtV6oAaeGir~P-x-nYhR03fDYCwjfrpzo55CQy1aEhv6UkDCDRDc3S4qkuVlKM3FHtLWUKAGeN69PyDYarXxW9g4sKPQRZNdlWL0aMEMR53-ybc2Nw34CoYIA~VFb3cREiKykE2~47fRgUPX9td8q4QUMnkpsfyVh-vWFsA4dxd9DW8Bmvvkl~xPuSG6-QFxxgtwm1lDIisQkOFVW4L-JgLGx2cqvISBdDblIgUEF1ASFE6w__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Insertion of the BMP6 flanking enhancer region causes the overexpression of MAP3K14. (A) Heat maps displaying the number of read clouds shared between indicated regions on chromosome 6 (chr6) and chr17. The connected green and orange arrows schematically indicate the areas joined by the SV. The type of SV is indicated. (B) Schematic representation of the derivate chromosome and tracks showing the H3K27Ac signal (median ± standard deviation [SD]) in the regions involved in the SV. (C) Expression of MAP3K14. fa+ti, templated insertion occurring in a focal amplification.