Figure 4.
ROC analysis of highly discriminative miRNAs. The five miRNAs miRa-365-3p, miR-148a-3p, miR-122-5p, miR-378a-3p, and miR-192-5p were the most discriminative miRNAs for the probability of cGVHD based on the differential expression analysis and were detected in >75 patients. The figure demonstrates the ROC curves for these 5 miRNAs. (A) The AUC was 0.729 (95% CI, 0.612-0.846) for miR-365a-3p. (B) The AUC was 0.720 (95% CI, 0.603-0.837) for miR-148a-3p. (C) The AUC was 0.715 (95% CI, 0.596-0.834) for miR-122-5p. (D) The AUC was 0.732 (95% CI, 0.612-0.852) for miR-378a-3p. (E) The AUC was 0.688 (95% CI, 0.568-0.807) for miR-192-5p. (F) The figure demonstrates the correlation coefficients for the relative expression of the 5 miRNAs miR-365a-3p, miR-148a-3p, miR-122-5p, miR-378a-3p, and miR-192-5p.