Weekly vs intracycle dosing of romiplostim for CIT. (A) A graphical representation comparing weekly and intracycle dosing over multiple different types of chemotherapy regimens. (B) Median weekly platelet counts in a cohort of patients with solid tumors receiving standard weekly romiplostim dosing (n = 65, dark blue) vs intracycle romiplostim dosing (n = 57, light blue). Error bars represent interquartile ranges. Adapted with permission from Al-Samkari et al.⁵