Study schema.

(A) RIC regimen. Fludarabine was administered at the daily dose of 25  mg/m² from days −7 to −3 before HCT. Melphalan was given on day −2 at 140  mg/m² or 100  mg/m² for patients ≥60 years old. (B) MAC regimen consisted of daily fludarabine at 30  mg/m², from days −7 to −5 before HCT. Total body irradiation was administered in 8 fractions of 150 cGy, 2 times a day, from days −4 to −1, for a total of 1200 cGy. Graft source was PBSCs for both strata. ANC, absolute neutrophils count; G-CSF, granulocyte colony stimulating factor; TBI, total body irradiation.