Comparison of variants observed in MM and B-ALL for all samples based on data availability (seeTable 1 ). (A) Scatter plot indicating the VAFs for B-ALL (x-axis) and MM (y-axis) tumors (supplemental Table 1 for eligible samples and supplemental Table 2 for eligible variants). Arrows indicate variants in the TP53 gene. (B) Chromosome/FISH abnormalities between B-ALL (red) and MM (blue) tumors. Each row represents a single sample. Solid lines indicate gain or polyploidy in the associated chromosome (x-axis). Dashed lines indicate loss or monosomy in the associated chromosome (x-axis). (C) Top clone IgH analysis is plotted for B-ALL (red) and MM (blue) tumors. V-gene and J-gene alleles are provided on the x-axis. Peak height indicates clonality percentage based on sequencing reads.