Comparison of major findings on various genetic models of GSDMD deficiency on the course of CLP sepsis. Whole-body or neutrophil-only and platelet-only knockout ^(−/−) mice were studied. In some animals transfer of GSDMD-expressing neutrophils (^+/+) was performed. −, none or unchanged parameter; ↑, increased; ↓, decreased; Inflamm., proinflammatory; ox-mtDNA, oxidized mitochondrial DNA; ref., reference; nd, not determined.